A case report of sisters with complete androgen insensitivity syndrome. |
So Hee Lim, Sang Hun Lee, Jin Kyung Lee, Sung Hoon Kim, Hee Dong Chae, Chung Hoon Kim, Byung Moon Kang |
Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea. bmkang@amc.seoul.kr |
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Abstract |
The complete androgen insensitivity syndrome is a genetic disorder that phenotypicaly female with normal male karyotype 46XY. It is inherited in an X-linked, recessive fashion. The defect affecting the gene responsible for the androgen intracellular receptor, that abolishes the target cells response to testosterone. This is a rare case but recently we experienced two cases , sisters in same family, so we presented them with brief review of literature. |
Key Words:
Androgen insensitivity syndrome, Genetic disorder, 46XY |
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