A Case of Malignant Mixed Mullerian Tumor after radiation therapy for Cervical cancer.

Cho, Ick Min; Ha, Man Taek; Jeong, Myeong Seob; Lee, Sang Yoon; Shin, Jeong Kyu; Lee, Soon Ae; Lee, Jong Hak; Paik, Won Young

Case Report

Korean Journal of Obstetrics & Gynecology 2005;48(11):2710-2715.
Published online November 1, 2005.

A Case of Malignant Mixed Mullerian Tumor after radiation therapy for Cervical cancer.

Ick Min Cho, Man Taek Ha, Myeong Seob Jeong, Sang Yoon Lee, Jeong Kyu Shin, Soon Ae Lee, Jong Hak Lee, Won Young Paik

Department of Obstetrics and Gynecology, College of Medicine, Gyeongsang National University, Jinju, Korea. wypaik@gshp.gsnu.ac.kr

Abstract

Malignant mixed mullerian tumors (MMMT) are uncommon neoplasms of the female genital tract that histologically consist of malignant epithelial components and stromal components. Most MMMTs are found in postmenopausal women. The clinical course is very poor due to frequent metastasis and recurrence. Among the carcinogenic epidemiologic predisposing factors, the relationship of previous pelvic irradiation to subsequent development of a malignant mixed mullerian tumor has been reported in recent years. We are reporting a case of MMMT of the uterus which occured in a woman who received radiation therapy for cervical cancer 11 years before the present date.

Key Words: Malignant mixed mullerian tumor, MMMT, pelvic irradiation