A Case of Holoprosencephaly.

Kim, Mi Hee; Yang, Su Chin; Cho, Eun Na; Park, So Yang; An, Hyun Sook; Choi, Won Young

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Case Report

Korean Journal of Obstetrics & Gynecology 2002;45(9):1636-1640.
Published online September 1, 2002.

A Case of Holoprosencephaly.

Mi Hee Kim, Su Chin Yang, Eun Na Cho, So Yang Park, Hyun Sook An, Won Young Choi

Department of Obstetrics and Gynecology, Ilsin Christian Hospital, Busan, Korea.

Abstract

Holoprosencephaly is a complex abnormality of the forebrain that is postulated to derive from a failure in the diverticulation of the embryonic prosencephalon. Early antenatal diagnosis of holoprosencephaly is important to find out its severity, to predict its prognosis and to determine proper treatment according to its prognosis and severity. With recent development of high resolution ultrasonography, it is possible to detect a fetus with holoprosencephaly at early antenatal period. We report a case of alobar holoprosencephaly, diagnosed antenatally with its sonographic and autopsy finding.

Key Words: Holoprosencephaly

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