A Case of Verrucous Carcinoma of the Cervix During Pregnancy.

Lee, K J; Kim, Y T; Kim, S K; Kim, Y H; Jung, Y N; Lee, Y J

Original Article

Korean Journal of Obstetrics & Gynecology 1999;42(6):1368-1371.
Published online January 1, 2001.

A Case of Verrucous Carcinoma of the Cervix During Pregnancy.

K J Lee, Y T Kim, S K Kim, Y H Kim, Y N Jung, Y J Lee

Abstract

Verrucous carcinoma of the uterine cervix is a very rare lesion, especially during pregnancy. Verrucous carcinoma is a variant of squamous cell carcinoma with distinctive clinical and pathologic features. It is a typically slow-growing, locally invasive tumor with low potential for lymphatic metastasis and diagnostic difficulties still exist. Surgical wide resection is the mainstay of the treatment. Whether to include radical resection or pelvic lymph node dissection in the extent of surgery is still under debate. Verrucous carcinoma is resistant to radiotherapy and some cases of transformation to an aggressive anaplastic form following irradiation have been reported, but further evaluation accompanying controlled case studies are needed. We report a case of verrucous carcinoma of the uterine cervix in a 27-year-old woman. It was found during pregnancy and successfully treated by surgical intervention, and there has been no evidence of recurrence for 10 years after treatment.

Key Words: Verrucous carcinoma, uterine cervix, pregnancy