Lipomatous variant of angiomyofibroblastoma on the vulva: A case report.

Lee, Sung Jong; Chung, Youn Jee; Lee, Sung Hak; Choi, Youn Jin; Kim, Narinay; Son, Hyun Joo; Yoon, Joo Hee

doi:2010.53.9.851

Obstet Gynecol Sci > Volume 53(9); 2010 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2010;53(9):851-855.
DOI: https://doi.org/10.5468/kjog.2010.53.9.851 Published online September 1, 2010.

Lipomatous variant of angiomyofibroblastoma on the vulva: A case report.

Sung Jong Lee, Youn Jee Chung, Sung Hak Lee, Youn Jin Choi, Narinay Kim, Hyun Joo Son, Joo Hee Yoon

¹Department of Obstetrics and Gynecology, The Catholic University of Korea School of Medicine, Seoul, Korea. jhyoon@catholic.ac.kr
²Department of Hospital Pathology, The Catholic University of Korea School of Medicine, Seoul, Korea.

Abstract

Lipomatous variant of angiomyofibroblastoma is a rare tumor of the vulva. Most of cases are usually premenopausal and present with a slowly growing mass without pain. A 46-year-old woman presented with a swelling of the left labium major. The lesion was thought to be a Batholin's gland cyst or a lipoma preoperatively and a local excision was performed. The tumor was well demarcated and rubbery. On microscopic examination, the alternating hypercellular and edematous hypocellular component with abundant vessels was noted. A large amount of adipose tissue was scattered in the lesion. Stromal cells were positive for vimentin, estrogen receptor, and progesterone receptor and negative for desmin antibody immunostaining. The local excision was enough for complete treatment. No recurrence was noted for 7 months after surgery.

Key Words: Vulva, Angiomyofibroblastoma, Lipomatous variant