A case of lymphoepithelioma-like carcinoma of the uterine cervix.

Ki, Eun Young; Ro, Duck Yeong; Kim, Hyo Jin; Park, Byung Joon; Kim, Yong Wook; Kim, Tae Eung; Jung, Jae Keun; Lee, An Hi

Case Report

Korean Journal of Obstetrics & Gynecology 2009;52(1):115-119.
Published online January 1, 2009.

A case of lymphoepithelioma-like carcinoma of the uterine cervix.

Eun Young Ki, Duck Yeong Ro, Hyo Jin Kim, Byung Joon Park, Yong Wook Kim, Tae Eung Kim, Jae Keun Jung, An Hi Lee

¹Department of Obstetrics and Gynecology, The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Korea. duckyeong20@yahoo.co.kr
²Department of Pathology, The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Korea.

Abstract

Lymphoepithelioma-like carcinoma (LELC) of the uterine cervix, also called lymphoepithelioma or medullary carcinoma, is a very rare variant of squamous cell carcinoma. Histologically, the tumor is characterized by groups and nests of poorly differentiated tumor cells with abundant cytoplasm and ill-defined cell borders, surrounded by an intense chronic inflammatory infiltrate. Epstein-Barr virus (EBV) may be involved in the development of LELC but the exact role remains unclear. The relationship between human papillomavirus (HPV) and LELC of the uterine cervix has also not been reported. The prognosis of LELC of the uterine cervix seems to be better than that of cervical squamous cell carcinoma. We report a case of LELC of the uterine cervix with a brief review.

Key Words: Lymphoepithelioma-like carcinoma, Uterine cervix