Clinical significance of E. coli O26 isolates on urine specimen of urinary tract infection.

Yoo, Hang Jo; Joo, Won Duk; Kim, Mi Ryung; Lee, Soo Jeong; Koo, Bon Sang; Jeong, Joseph; Lee, Seon Ho; Kim, Sung Ryul

Original Article

Korean Journal of Obstetrics & Gynecology 2008;51(9):1025-1029.
Published online September 1, 2008.

Clinical significance of E. coli O26 isolates on urine specimen of urinary tract infection.

Hang Jo Yoo, Won Duk Joo, Mi Ryung Kim, Soo Jeong Lee, Bon Sang Koo, Joseph Jeong, Seon Ho Lee, Sung Ryul Kim

¹Department of Obstetrics & Gynecology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. doctorku@hanmail.net
²Department of Laboratory Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.

Abstract

OBJECTIVE
Escherichia coli (E. coli) O26 has been the most common type of non-O157 human isolates and it has been related with urinary tract infection and its sequelae. So we investigated the clinical significance of E. coli O26 among the cases of urinary tract infection. METHODS: From January, 2005 to December, 2007, the 22 E. coli isolates that were related with urinary tract infection were analyzed. The isolates were identified biochemically by Vitek 1. We performed antisera test by O157, O26, O111 diagnostic antisera about the 22 E. coli isolates. We reviewed clinical history of the same patients retrospectively. RESULTS: 331 E. coli isolates in the urine specimen were isolated from January, 2005 to December, 2007. 175 E. coli isolates that were related with urinary tract infection were analyzed by O157, O26, O111 antisera test. As a result, 22 isolates (13.5%) were O26 antisera positive. There were 8, 3, and 2 cases of watery diarrhea, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura repectively. CONCLUSION: In our study, because E. coli O26 was pathogenic and developed major complications, we concluded that patients with urinary tract infection with E. coli. should examine the antisera test about E. coli O157 and O26.

Key Words: Escherichia coli, O157, O26, Anti-sera test, Urinary tract infection