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Korean Journal of Obstetrics & Gynecology 2007;50(8):1057-1063.
Published online August 1, 2007.
Current status of application of the secondary cytoreductive surgery for patients with epithelial ovarian carcinomas.
Moon Hong Kim, Sang Il Park
Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences, Seoul, Korea. garymh@kcch.re.kr
Abstract
Recurrent ovarian cancer has been considered as a difficult disease to treat despite the rapid development of various chemotherapeutic agents and surgical techniques for several decades. Many investigators tried to establish the optimal triage for treat recurrent or persistent disease applying not only salvage regimen but also debulking surgery. We reviewed many literature concerning the surgical approaches for patients with primary treatment failure to outline the treatment scheme. Most of authors agrees that optimal or even maximal cytoreduction enables survival benefit of patients with refractory disease while the biologic characteristics of tumor may not affect the prognosis.
Key Words: Ovarian neoplasms, Secondary cytoreduction, Debulking surgery, Salvage therapy


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