Korean J Obstet Gynecol Search

CLOSE


Korean Journal of Obstetrics & Gynecology 2006;49(1):113-121.
Published online January 1, 2006.
Analysis of factors to affect on MR assessment of myometrial invasion and cervical involvement in endometrial cancer.
Ji Young Ahn, Chong Mi Yi, Tae Sung Lee, Seok Bong Koh, Young Chan Park, Kyung Jae Jung, Hun Kyu Oh, Youn Seok Choi
1Department of Obstetrics and Gynecology, College of Medicine, Daegu Catholic University, Daegu, Korea. drcys@cu.ac.kr
2Department of Radiology, College of Medicine, Daegu Catholic University, Daegu, Korea.
3Department of Pathology, College of Medicine, Daegu Catholic University, Daegu, Korea.
Abstract
OBJECTIVE
The aim of this study was to assess the depth of myometrial invasion and cervical involvement by endometrial cancer using magnetic resonance imaging (MRI). METHODS: Forty three patients with histological diagnosis of endometrial cancer were studied with the results of MRI at 1.5T and subsequently underwent staging operation. The MRI results were compared with pathologic results. Presence of large polypoid tumors, leiomyoma, adenomyosis, distension of uterine cavity by large tumor, atrophy of uteri, utetrine anomalies and tumor protruding into the cervical canal were analyzed. RESULTS: On review, the sensitivity for the detection of myometrial invasion was 93.5%, specificity 58.3%, positive predictive value (PPV) 85.3% and negative predictive value (NPV) 77.8%. For the detection of deep myometrial invasion, sensitivity was 87.5%, specificity 85.7%, PPV 58.3% and NPV 96.8%. For the detection of cervical involvement, sensitivity was 100%, specificity 92.9%, PPV 25%, NPV 100%. Distension of uterine cavity by large tumor (p=0.009) and adenomyosis (p=0.041) were associated with incorrect MRI assessment of myometrial invasion. For cervical involvement, tumor protruding into the cervical canal was associated but did not reach statistical significance (p=0.062). CONCLUSION: MRI scans as reported offered some clinical benefit in preoperative assessment of endometrial cancer, but for assessment of cervical involvement, showed low PPV. When present, distension of uterine cavity by large tumor and adenomyosis may make it difficult to assess myometrial invasion at MR imaging.
Key Words: Magnetic resonance imaging, Endometrial carcinoma, Myometrial invasion, Cervical invasion


ABOUT
ARTICLE & TOPICS
Article category

Browse all articles >

Topics

Browse all articles >

BROWSE ARTICLES
POLICY
FOR CONTRIBUTORS
Editorial Office
4th Floor, 36 Gangnam-daero 132-gil, Gangnam-gu, Seoul 06044, Korea
Tel: +82-2-3445-2382    Fax: +82-2-3445-2440    E-mail: journal@ogscience.org                

Copyright © 2021 by Korean Society of Obstetrics and Gynecology. All rights reserved.

Developed in M2community

Close layer
prev next