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Korean Journal of Obstetrics & Gynecology 2006;49(1):31-39.
Published online January 1, 2006.
Associated anomalies and perinatal outcomes in the fetus with single umbilical artery.
Soo Kon Kim, Jong Seok Kim, Ji Young Kang, Yun Dan Kang, Man Chul Park
Department of Obstetrics and Gynecology, Dankook University, College of Medicine, Chan-an, Korea. parkmanc@hanmail.net
To evaluate the pattern of associated structural anomalies, perinatal outcomes and obstetrical complications in fetuses with single umbilical artery. METHODS: 27 fetuses with a single umbilical artery were detected between May 1995 and June 2005 at our hospital. All medical records were reviewed for maternal demographics, associated anomalies, karyotypic analysis, pregnancy complications and perinatal outcome. RESULTS: Of the 27 fetuses, 1 (3.7%) was terminated and 1 (3.7%) was expired. 13 fetuses (48.1%) had an associated structural anomalies. The structural anomalies found in association with single umbilical artery were in the cardiovascular system (6 cases, 46.2%), urogenital system (6 cases, 46.2%), central nervous system (3 cases, 23.1%), neuromuscular system (3 cases, 23.1%) and gastrointestinal system (1 case, 7.7%). 6 cases (46.2%) among these had multiple malformations. Karyotypic analyses were available only in 3 cases and one of these was chromosomally abnormal. CONCLUSION: Scanning the umbilical cord should be one of the essential parts of the second trimester ultrasonographic examination. When single umbilical artery is detected, a detailed ultrasonographic examination including fetal echocardiography and fetal karyotyping should be recommended for search of associated structural and chromosomal abnormalities.
Key Words: Single umbilical artery, Congenital anomalies, Perinatal outcomes

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