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Korean Journal of Obstetrics & Gynecology 2005;48(5):1294-1305.
Published online May 1, 2005.
Relative influence of age and menopause on total and regional Body composition changes measured by DEXA in Postmenopausal Women.
Soo Hyun Cho, Hyoung Moo Park
1Obesity Clinic, Korea.
2Department of Family Medicine, Yongsan Hospital, Chung-Ang University, Seoul, Korea.
3Department of Obstetrics and Gynecology, Yongsan Hospital, Chung-Ang University, Seoul, Korea. hmpark@hananet.net
Abstract
OBJECTIVE
In Korea, only a few reports were introduced about body fat mass of women with using the Dual energy X-ray absorptiometry (DEXA), highly sensitive and specific measurement for fat mass analysis. This study was carried out to determine whether total and regional body composition changes measured by DEXA were more related to age or to menopause. METHODS: One hundred fifteen postmenopausal women who had never received estrogen replacement therapy were enrolled in Menopausal Clinic from January 2001 to April 2002. BMD and body composition were measured by DEXA. The proportions of android and gynoid fat were calculated in all women and differences were sought by ANOVA test, Pearson correlation and multiple linear regression. RESULTS: They were classified as perimenopausal women (n=31), young postmenopausal women (n=60) or old postmenopausal women (n=24). Bone mineral content (BMC), BMD, leg lean body mass and gynoid fat were significant differences among three groups. In multiple linear regression, age was a predictor of total, trunk and leg BMC (p<0.01), total, L2-4 and proximal femur BMD (p<0.01), total, arm and trunk fat percentage of total body mass and trunk regional fat percentage of regional tissue (p<0.05), whereas years since of age was not a predictor of any of the body composition variables. CONCLUSION: The findings of this study suggest that BMC, BMD and body fat distribution with a shift toward a more central location in postmenopausal women. This change appears to be more related to age than to menopause.
Key Words: Body composition, Fat, Dual energy X-ray absorptiometry (DEXA), Age, Menopause


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