A case of prenatally detected bilateral multicystic dysplastic kidney with chromosomal abnormality.

Yang, Hwan Ju; Kim, Hyun Young; Chung, Meong Ja; Lee, Jeong Heon; Jeong, Young Ju; Jin, So Ja; Kim, Jong Duk

Case Report

Korean Journal of Obstetrics & Gynecology 2004;47(10):1987-1990.
Published online October 1, 2004.

A case of prenatally detected bilateral multicystic dysplastic kidney with chromosomal abnormality.

Hwan Ju Yang, Hyun Young Kim, Meong Ja Chung, Jeong Heon Lee, Young Ju Jeong, So Ja Jin, Jong Duk Kim

¹Department of Obstetrics and Gynecology, Chonbuk National University Medical School, Jeonju, Korea.
²Department of pathology, Chonbuk National University Medical School, Jeonju, Korea.

Abstract

Multicystic dysplastic kidney (MCDK) is one of the most common causes of an abdominal mass in infants and it is the cystic anomaly most frequently identified antenatally by prenatal ultrasonography. The incidence of bilateral MCDK incidence is 1 in 5,000-10,000 births, but the prognosis is very poor due to association with other anomalies as well as chromosomal abnormalities. Recently, we performed prenatal diagnosis on a 26-year-old primigravida after a detection of oligohydramnios with bilateral MCDK on fetal ultrasonographic examination at 24 weeks gestation. Chromosomal analysis of the amniotic fluid cell cultures revealed a 46, XX, t(15;17)(p3;p12) karyotype. Bilateral MCDK was confirmed after autopsy, therefore we report this case with a review of brief literatures.

Key Words: Multicystic dysplastic kidney, Tranaslocation, Prenatal diagnosis