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Korean Journal of Obstetrics & Gynecology 2004;47(10):1880-1885.
Published online October 1, 2004.
Comparative Study of Single-dose Prophylactic Antibiotics after Cord Clamping Vs. Multi-dose Postoperative Antibiotics in Operative Complications after Elective Cesarean Section.
Jun Kil Baek, Won Sik Lee, Joo Myung Kim, In Ho Lee, Yeon Kyung Cho, Jae Hyug Yang
Department of Obstetrics and Gynecology, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Abstract
OBJECTIVE
To compare single-dose prophylactic antibiotics after cord clamping with multi-dose postoperative antibiotics in operative complications after elective cesarean section. METHODS: Forty-five women undergoing elective cesarean section had 1g cefazolin administration after umbilical cord clamping. Forty-five women was control group who had antibiotics administration postoperatively 4 times 1 g cefazolin and 5 days more per oral. Postoperative complication including febrile morbidity, wound infection, endometritis, urinary tract infection, pneumonia were recorded, as were the duration of hospital stay and the need for therapeutic antibiotics. RESULTS: Postoperative complication incuding febrile morbidity, wound infection, endometritis, urinary tract infection, pneumonia had no difference between two groups significantly. Also, their hospital stay had no difference significantly. CONCLUSION: Single-dose prophylactic antibiotics administration after cord clamping in elective cesarean section is considered to have no difference in comparison with multi-dose post-operative administration. Single-dose prophylactic antibiotics administration after cord clamping will reduce side effect of drugs and resistance. Also it will provide better cost effectiveness.
Key Words: Cesarean section, Prophylactic antibiotics
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