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Korean Journal of Obstetrics & Gynecology 2004;47(5):988-991.
Published online May 1, 2004.
A Case of Edward Syndrome with Choroid Plexus Cyst.
Hyun Jung Lee, Kyung Jin Hwang, Ho Jin Choi, Ho Sun Chang, Yong Buem Kim, Pil Je Cho
Grace Women's Hospital, Korea.
Abstract
Trisomy 18 is the second most common chromosomal anomaly which reach to live birth next to Down syndrome. Several methods were proposed to screen patients on the risk of Edward syndrome like maternal serum levels of total human chorionic gonadotropin (hCG), alpha-fetoprotein (AFP) and unconjugated estriol or free beta hCG with AFP, but the serum screening has only 67% detection rate with a 7.2% of false positive rate. Therefore, in order to overcome the limitations which the serum markers have, detailed ultrasound examination is also necessary and sensitivity of 80% was reported. We report a case of Trisomy 18 fetus in which choroid plexus cyst was the only abnormal sonographic finding.
Key Words: Edward syndrome, Choroid plexus cyst


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