A Case of Caudal Regression Syndrome in the Newborn of the Diabetic Mother.

Park, Cheol Hoon; Rho, Duk Young; Kim, Yong Wook; Kim, Tae Ung; Joung, Jae Gun

Case Report

Korean Journal of Obstetrics & Gynecology 2004;47(2):405-408.
Published online February 1, 2004.

A Case of Caudal Regression Syndrome in the Newborn of the Diabetic Mother.

Cheol Hoon Park, Duk Young Rho, Yong Wook Kim, Tae Ung Kim, Jae Gun Joung

Department of Obstetrics and Gynecology, College of Medicine, Catholic University, Seoul, Korea.

Abstract

The Caudal regression syndrome is characterized by sacrococcygeal or lumbosacrococcygeal agenesis, of variable extent, most often accompanied by multiple musculoskeletal abnormalities of the pelvis and legs. It is rare fetal complication of diabetic pregnancy. Although the exact teratogenic mechanism is not known, hyperglycemia appears to play a crucial role as a teratogen. Strict control of diabetes preconceptually and in early pregnancy is presumed to reduce the risk of occurrence. We report a case of caudal regression syndrome detected by pelvic radiography and MRI in the newborn of the diabetic mother.

Key Words: Caudal regression syndrome, Diabetes