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Korean Journal of Obstetrics & Gynecology 2004;47(1):178-182.
Published online January 1, 2004.
A Case of Placental Site Trophoblastic Tumor.
Jun Hyung Kim, Ki Hong Chang, Sang Tae Ahn, Hee Jae Joo, Joung Pil Lee, Hee Sug Ryu
1Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea.
2Department of Anatomic Pathology, Ajou University School of Medicine, Suwon, Korea.
Abstract
Placntal site trophoblastic tumor (PSTT) has been demonstrated to be a rare form of gestational trophoblastic tumor (GTT). Kurman (1976) et al recognized this disease as Trophoblastic pseudotumor and they thought it to be a benign exaggerated placental site reaction, but Twiggs et al (1981) reported a patient who died of widespread metastasis. Death has been reported in 2 of 14 cases due to metastatic disease, and therefore it is thought to have a malignant course and metastatic potential. It may occur at any age during the reproductive age but usually occurs in relation to second or subsequent pregnancies (a normal pregnancy, an abortion, or a molar pregnancy) rather than primipara. PSTT can metastasis to the brain, lung, liver, vagina and bladder. Larsen et al (1991) report metastasis rate about 10%. It produces little hCG and larger quantities of hPL. We experienced a case of PSTT after normal delivery, which was diagnosed and operated on in our hospital, and report this case with a brief review of literatures.
Key Words: Placental site trophoblastic tumor


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