Effects of Preconceptional Sperm Exposure to Female Genital Tract on the Development of Hypertensive Diseases During Pregnancy.

Kim, Ki Dong; Lee, Joon Ho; Lee, Si Eun; Shim, Soon Sup; Ku, Seung Yup; Park, Joong Shin; Jun, Jong Kwan; Kim, Seok Hyun; Choi, Young Min; Yoon, Bo Hyun; Syn, Hee Chul

Original Article

Korean Journal of Obstetrics & Gynecology 2004;47(1):104-108.
Published online January 1, 2004.

Effects of Preconceptional Sperm Exposure to Female Genital Tract on the Development of Hypertensive Diseases During Pregnancy.

Ki Dong Kim, Joon Ho Lee, Si Eun Lee, Soon Sup Shim, Seung Yup Ku, Joong Shin Park, Jong Kwan Jun, Seok Hyun Kim, Young Min Choi, Bo Hyun Yoon, Hee Chul Syn

Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

OBJECTIVE
This study was performed to know whether toxemia occurred more frequently in pregnancy which is achieved despite of azoospermia or severe oligospermia. METHODS: We selected 31 women who underwent surgical sperm aspiration and ICSI at Seoul National University Hospital (SNUH) from 1995 to 2001 and pregnancy continued over 20 gestational age as study group. And as a comparison group, 19 women who underwent ICSI at SNUH from 1995 to 2001 with no semen analysis abnormality and pregnancy continued over 20 gestational age were selected. The incidence of toxemia in both groups was observed. RESULTS: There were no differences in the incidence of gestational hypertension and preeclampsia between groups (RR=3.46, 95%CI 0.37-32.18) (RR=0.91, 95%CI 0.14-6.02). CONCLUSION: No association was observed between preconceptional sperm exposure to female genital tract and the incidence of toxemia.

Key Words: Toxemia, Azoospermia, Oligospermia, Preeclampsia, Pregnancy induced hypertension