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Korean Journal of Obstetrics & Gynecology 2003;46(4):825-829.
Published online April 1, 2003.
A Case of Prenatally Diagnosed Fetal Unilateral Renal Agenesis with Contralateral Renal Hypoplasia.
Min Jeong Kim, Hyun Young Ahn, Jee Hyun Lee, Hee Bong Moon, Gui Se Ra Lee, Sa Jin Kim, Jong Chul Shin, Gong Gu Ra
Department of Obstetrics and Gynecology College of Medicine, Catholic University of Korea, Seoul, Korea.
Abstract
Renal agenesis is a disorder characterized by the congenital absence of one or both kidneys due to complete failure of the kidney to form. The syndrome of renal agenesis is severe oligohydramnios, amnion nodosum, flattened face, low-set and floppy ears, and bilateral pulmonary hypoplasia. Bilateral renal agenesis occurs in 0.1 to 0.3 per 1000 births and unilateral involvement occurs in 1 in 500 to 1 in 1300 live births.1,2 Bilateral renal agenesis is an invariably lethal condition, and is associated in more than half of the affected individuals with malformations of the genitourinary tract, cardiovascular system, vertebral bodies or imperforated anus.2 Accurate diagnosis in the mid-trimester permits the parents to allow elective termination. However, the nearly absent amniotic fluid makes an accurate assessment of fetal kidney difficult. We present a case of unilateral renal agenesis with contralateral renal hypoplasia, diagnosed by ultrasonography after amnioinfusion at 21 weeks gestation.
Key Words: Renal agenesis, Severe oligohydramnios, Prenatal diagnosis


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