A Case of Advanced Squamous Cell Carcinoma Arising in Mature Cystic Teratoma of the Ovary.

Kang, Woong Sun; Lee, Chul Min; Lim, Sung Jig; Cho, Yong Kyoon; Choi, Hoon; Kim, Bok Rin; Lee, Hong Kyoon

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(2):474-478.
Published online February 1, 2003.

A Case of Advanced Squamous Cell Carcinoma Arising in Mature Cystic Teratoma of the Ovary.

Woong Sun Kang, Chul Min Lee, Sung Jig Lim, Yong Kyoon Cho, Hoon Choi, Bok Rin Kim, Hong Kyoon Lee

¹Department of Obstetrics and Gynecology, College of Medicine, Inje University, Korea.
²Department of Pathology, College of Medicine, Inje University, Korea.

Abstract

Mature cystic teratoma comprises approximately 10-20% of all ovarian neoplasms and malignant transformation from mature cystic teratoma is reported to be less than 2%. Squamous cell carcinoma is the most frequent malignancy (80%) arising in mature cystic teratoma followed by sarcoma (7-8%), adenocarcinoma (6-7%), carcinoid tumor, melanoma, choriocarcinoma (1-2%). Prognosis of squamous cell carcinoma in mature cystic teratoma is reported much poorer than that of epithelial ovarian cancer with the same stage. We experienced one case of squamous cell carcinoma arising in mature cystic teratoma.

Key Words: Mature cystic teratoma, Squamous cell carcinoma, Malignant transformation