A Case of Anencephaly Associated with Twin Pregnancy Conceived by In Vitro Fertilization and Embryo Transfer.

Joung, Jin Suk; Kim, Kwang Koog; Park, Ji Hyeun; Bae, Seong Keun; Kee, Hyun Seon; Lee, Ju Young; Kim, Ji Hyang; Park, Jie Won

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(2):435-439.
Published online February 1, 2003.

A Case of Anencephaly Associated with Twin Pregnancy Conceived by In Vitro Fertilization and Embryo Transfer.

Jin Suk Joung, Kwang Koog Kim, Ji Hyeun Park, Seong Keun Bae, Hyun Seon Kee, Ju Young Lee, Ji Hyang Kim, Jie Won Park

Department of Obstetrics and Gynecology, College of Medicine Pochon CHA University, Seoul, Korea.

Abstract

Twin pregnancies are increasing these days due to recent development of the technology in treating infertility and twin pregnancies tend to cause more congenital anomaly than singleton pregnancies do. Although anencephaly is not uncommon, occurring in about one in every 1,000 births, anencephaly developed in a twin pregnancy is very rare. We experienced a twin pregnancy which consisted of an anencephalic fetus and a normal one. This pregnancy was conceived by IVF and ET. This pregnancy was continued without having special problems and was delivered at 36 weeks of gestation by cesarean section due to SROM (spontaneous rupture of membrane). The anencephalic fetus weighed 1,430 gm and was already dead in the uterus. The other weighed 2,660 gm and showed no external anomaly. Its Apgar score was 8 in 1 minute and 9 in 5 minute. The pregnancy resulted in a cesarean section delivery of one dead anencephalic fetus and one normal healthy fetus. We report with a brief review of literature a case of a twin pregnancy, conceived by IVF and ET, in which anencephaly was associated with a normal fetus.

Key Words: Twin, Anencephaly, IVF and ET