Genetic amniocentesis after multifetal pregnancy reduction.

Kim, Kwang Koog; Park, Ji Hyeun

Original Article

Korean Journal of Obstetrics & Gynecology 2002;45(11):1946-1950.
Published online November 1, 2002.

Genetic amniocentesis after multifetal pregnancy reduction.

Kwang Koog Kim, Ji Hyeun Park

Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University, seoul, Korea.

Abstract

OBJECTIVE
This study is directed to evaluate the pregnancy loss rate resulting from genetic amniocentesis after multifetal pregnancy reduction. METHODS: From March 1998 to April 1999, total 145 patients with multifetal pregnancy were included in this study. Pregnancy loss in a study population of 44 patients who underwent genetic amniocentesis after multifetal pregnancy reduction were compared with a control group of 99 patients who did not have genetic amniocentesis after multifetal pregnancy reduction. RESULTS: The pregnancy loss rate in patients who underwent genetic amniocentesis after multifetal pregnancy reduction was 2.2% (1/44) compared with 4% (4/99) in the controls (P>.05). In the study group, one woman lost her pregnancy at 19 weeks' gestation, 3 weeks after the genetic amniocentesis, and the predisposing factor was spontaneous rupture of membranes. CONCLUSION: Genetic amniocentesis following multifetal pregnancy reduction does not increase the risk of pregnancy loss.

Key Words: Multifetal pregnancy reduction, Amniocentesis, Pregnancy loss