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Korean Journal of Obstetrics & Gynecology 2002;45(5):860-863.
Published online May 1, 2002.
A Case of Globozoospermia Conceived by Intracytoplasmic Sperm Injection.
Yoon Sung Nam, Jie Ohn Sohn, Hyun Kyoo Kim, Seung Bum Kim, Mi Kyung Chung, Kwang Yul Cha
1Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
2Department of Andrology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
3Department of Embryology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
Abstract
Human sperm are not only pleomorphic but also tend to show large numbers of obvious abnormalities that may be associated with infertility. It is known that the greater the numbers of abnormalities present in each sperm (teratozoospermic index) relates closely to abnormalities in sperm function and the presence of infertility. The variation in morphology that may be seen among human sperm involve the head, midpiece and tail. An oval head is deemed to be normal but many shape and size variations can be seen in an ejaculate, and these include large, small or tapering heads. Amorphous heads are now known to be associated with chromosomal anomalies and a sperm may even show the presence of a double head. Another anomaly of sperm morphology that is occasionally seen is the abnormality known as globozoospermia. In this condition, the sperm head lacks an acrosome and, as a consequence, the head of each spermatozoon becomes rounded. We have experienced a case of globozoospermia which was conceived by intracytoplasmic sperm injection. So we report this case with a brief review of literatures.
Key Words: Intracytoplasmic sperm injection, Globozoospermia


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