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Korean Journal of Obstetrics & Gynecology 2002;45(4):723-727.
Published online April 1, 2002.
A case of neonatal lupus syndrome with congenital complete heart block.
Seo Ho Chung, Young Lee, Yeon Hee Cheon, In Cheul Jung, Won Sik Yoon, Jae Sung Lee, Chong Seong Yi, Jong Kun Lee, Soo Pyung Kim
Department of Obstetrics and Gynecology, Catholic University Medical College, Seoul, Korea.
Abstract
The neonatal lupus syndrome is characterized by skin lesions, hepatic and hematologic abnormalities and congenital heart block. Congenital heart block which is believed to be caused by transplacental passage of the anti-Ro (SSA)/La (SSB) antibodies from mother to infant, is known to occur in 1 in 20,000 live births. In contrast to other manifestation of neonatal lupus syndrome, which usually subside within 6 months after birth, congenital heart block is a permanent and potentially fatal complication. We experienced a case of neonatal lupus syndorme with congenital complete heart block in a newborn of asyptomatic mother with anti-Ro (SSA)/ La (SSB) antibodies.
Key Words: neonatal lupus syndrome, congenital complete heart block, anti-Ro (SSA)/La (SSB) antibodies


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