A Case of Malignant Mixed Mullerian Tumor of Uterus Developed After Pelvic Irradiation.

Yum, Yoon Seok; Lim, Myong Cheol; Huh, Chu Yeop; Kim, Seung Bo

Case Report

Korean Journal of Obstetrics & Gynecology 2001;44(12):2367-2371.
Published online December 1, 2001.

A Case of Malignant Mixed Mullerian Tumor of Uterus Developed After Pelvic Irradiation.

Yoon Seok Yum, Myong Cheol Lim, Chu Yeop Huh, Seung Bo Kim

Department of Obstetrics and Gynecology, College of Medicine, Kyung Hee University, Seoul, Korea.

Abstract

Mixed mullerian tumors are uncommon tumor and highly malignant containing epithelial and mesenchymal component. Most of these tumors arise spontaneously in the sixth to eight decades of life, but a certain proportion are known to occur in women who have received pelvic irradiation from five to 30 years before for benign or malignant disease. This apparent association has led to the belief that pelvic irradiation somewhat increase the neoplastic potential of the uterine corpus, although the precise role of irradiation in the genesis of uterine neoplasia remain uncertain. We experienced one case of malignant mixed mullerian tumor of uterus developed after pelvic irradiation. So we report the case with a brief review of literature.

Key Words: Malignant Mixed Mullerian Tumor, Irradiation