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Korean Journal of Obstetrics & Gynecology 2001;44(10):1909-1912.
Published online October 1, 2001.
A Case of Wernicke's Encephalopathy associated with Hyperemesis Gravidarum.
Yong Seok Choi, Jong Oh Kim, Seong Lim Lee, Seung Kyu Song, Bong Choon Jo
Department of Obstetrics and Gynecology, Dae Rim Saint Mary's Hospital, Seoul, Korea.
Abstract
Hyperemesis gravidarum is characterized by severe nausea, vomiting followed by weight loss, dehydration, electrolyte imbalance and acid-base derangements. Its treatment was composed of adequate fluid therapy, electrolyte replacement and nutrient supply. In severe case, it also leads to a variety of neurological symptoms including confusion, gait disturbance and nystagmus, possibly due to thiamine deficiency and may result in so called Wernicke's disease. We have experienced a case of Wernicke's encephalopathy associated with severe hyperemesis gravidarum and this case is presented with a brief review of literature.
Key Words: Hyperemesis gravidarum, Wernicke's encephalopathy


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