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Korean Journal of Obstetrics & Gynecology 2001;44(9):1744-1760.
Published online September 1, 2001.
The prenatal care and delivery in a pregnant woman complicated by hereditary sideroblastic anemia.
Geon Young Lee, Young Sim Lee, In Bai Chung, Sang Hag Lee, Byung Wook Kim, Hyuk Dong Han, Young Jin Lee
Department of Obstetrics and Gynecology, Wonju medical college, Yonsei University, Wonju, Korea.
Abstract
Anemia is the one of the most common complications among pregnant women, but sideroblastic anemia is very rare condition. The sideroblastic anemias have diverse etiologies but have in common an impaired biosynthesis of heme in the erythroid cells of the marrow. The ringed sideroblasts in the bone marrow aspirate is diagnostic hallmark of sideroblastic anemia. We report here a prenatal care and delivery in a pregnant woman complicated by hereditary sideroblastic anemia. This patient was treated with 200mg of pyridoxine per day during entire pregnancy period and further more, 4mg of oral folate per day was supplemented because concomitant folate deficiency is frequent in case of erythroid hyperplasia. Intermittently, the transfusions of packed red blood cells were required to maintain the hemoglobin level in the 9 to 10gm/dl range. We have experienced healthy maternal and perinatal outcome.
Key Words: Sideroblastic anemia, Pregnancy, Pyridoxine


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