A Case of Complete Remission by Combination Chemotherapy with BEP Regimen after Operation in Endodermal Sinus Tumor of Ovary.

Choi, Young Ryoul; Lee, Jae Ju; Song, Jung Ho; Jeon, Sung Chul; Kang, Ji Hoon; Cho, Dae Hyun; Lee, Mi Sun

Case Report

Korean Journal of Obstetrics & Gynecology 2001;44(9):1719-1723.
Published online September 1, 2001.

A Case of Complete Remission by Combination Chemotherapy with BEP Regimen after Operation in Endodermal Sinus Tumor of Ovary.

Young Ryoul Choi, Jae Ju Lee, Jung Ho Song, Sung Chul Jeon, Ji Hoon Kang, Dae Hyun Cho, Mi Sun Lee

¹Department of Obstetrics and Gynecology, Sun General Hospital, Dae Jeon, Korea.
²Department of Pathology, Sun General Hospital, Dae Jeon, Korea.

Abstract

Endodermal sinus tumor (EST) has also been referred to as yolk sac carcinoma because they are derived from the primitive yolk sac. These lesions are the third most frequent malignant germ cell tumor of the ovary. Patient with EST have a median age of 18 years, but approximately one third of the patients are premenarchal at the time of initial presentation. Abdominal and/or pelvic pain is the most frequent presenting symptom, most EST secrete AFP. Radical surgery has not been helpful, but recent advances in treating the EST of the ovary with the combination chemotherapy after unilateral salpingo-oophorectomy result in improvement of the prognosis. We had experienced a case of endodermal sinus tumor of 36 years old woman. So, we report this case with brief review of the literature.

Key Words: EST, BEP