A Case of Nonimmune Hydrops Fetalis with neuroblastoma.

Hwang, Dae Jin; Yoo, Young Ok; Lee, Hyung Geun; Jo, Hyung Gwon; Park, Dong Choon; Jung, Dae Young; Kim, Dae Hoon; Kim, Soo Pyung; Namgoong, Sung Eun

Case Report

Korean Journal of Obstetrics & Gynecology 2001;44(1):171-175.
Published online January 1, 2001.

A Case of Nonimmune Hydrops Fetalis with neuroblastoma.

Dae Jin Hwang, Young Ok Yoo, Hyung Geun Lee, Hyung Gwon Jo, Dong Choon Park, Dae Young Jung, Dae Hoon Kim, Soo Pyung Kim, Sung Eun Namgoong

¹Catholic University of Korea College of Medicine, Dept of OB & GYN St. Vincent 's Hospital, Suwon, Korea.
²St.Mary 's Hospital, Seoul Korea.
³Kangnam St.Marys Hospital, Seoul ,Korea.

Abstract

Hydrops fetalis is diagnosed when abnormal fluid collections are manifest in two or more fetal compartmnets including abdominal ascite, pleural effusion, percardial effusion, skin edema, polyhydroamniosis and placental edema. Although fetal hydrops was historically most commonly associated with Rh blood group isoimmunization, the availability of Rh immunoglobulin has increased the proportion of fetuses affected due to nonimmune etiologies. Neuroblastoma is a malignant tumor which originates in the autonomous nervous system. Congenital neuroblastoma is the most common solid malignant tumor of the neonatal period, incidence ranges 1:10,000 of all live births, retroperitoneal space being the most frequent localization. We have experienced a case of nonimmune hydrops fetalis with neuroblastoma at 32 weeks of gestation in 39 year old woman and reported that with brief review of related literatures.

Key Words: Nonimmune hydrops fetalis, neuroblastoma