Twin Pregnancy and Delivery After Intracytoplasmic Sperm Injection Followed by Calcium Ionophore with Spermatozoa from a Globozoospermic Man: A Case Report.

Lee, Yong Chan; Lee, Young Hee; Joo, Jae Hong; Yoon, San Hyun; Lim, Jin Ho

Case Report

Korean Journal of Obstetrics & Gynecology 2000;43(4):739-741.
Published online January 1, 2001.

Twin Pregnancy and Delivery After Intracytoplasmic Sperm Injection Followed by Calcium Ionophore with Spermatozoa from a Globozoospermic Man: A Case Report.

Yong Chan Lee, Young Hee Lee, Jae Hong Joo, San Hyun Yoon, Jin Ho Lim

Abstract

Our purpose is to describe a successful twin pregnancy and delivery after intracytoplasmic sperm injection (ICSI) followed by calcium ionophore with spermatozoa from a globozoospermic man. On the second attempt of ICSI, all of eight metaphase II oocytes were fertilized with treatment with calcium ionophore. Day 3 transfer of six normally developing embryos resulted in an ongoing twin pregnancy, and two preterm healthy babies were born in the 33th week of gestation. To the best of our knowledge, this is the first report of pregnancy and delivery after ICSI followed by calcium ionophore with spermatozoa from a globozoospermic man in Korea.

Key Words: globozoospermia, intracytoplasmic sperm injection, calcium ionophore, pregnancy