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Korean Journal of Obstetrics & Gynecology 1999;42(11):2474-2479.
Published online January 1, 2001.
Screening of high risk pregnancy using maternal serum triple markers.
Moon Whan Im, Sang Hoon Han, Ji Hyeun Park, Kwan Young Oh, Young Koo Lim, Eun Seop Song, Seung Kwon Kho, Byoung Ick Lee, Jong Wha Kim, Woo Young Lee
Abstract
OBJECTIVE
Our purpose was to determine whether abnormal triple marker in the second trimester may be associated with adverse pregnancy outcomes. METHODS: Between November 1996 and April 1998, we evaluated 1,158 pregnant women undergoing second trimester triple marker screening tests who delivered at our hospital. The pregnancy outcomes of 48 women with false positive screens were compared with 1,158 screen negative controls. The pregnancy outcomes were obtained from hospital delivery records. RESULTS: Women with abnormal triple marker showed increased risks for low birth weight(p<0.01). But there was no significant differences between study and control groups with respect to preterm labor, pregnancy induced hypertension, oligohydroamnios, premature rupture of membrane, placenta previa, abruptio placenta, fetal death in utero. CONCLUSION: Abnormal triple marker in the second trimester was associated with low birth weight.
Key Words: Abnormal triple marker, False positive screens, Adverse pregnancy outcome


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