| A Case of Twin Pregnancy with Complete Hydatidiform Mole and Coexisting Fetus Following IVF-ET. |
|
E H Kang, H S Chu, H D Chae, J H Kim, B M Kang, Y S Chang |
|
|
| Abstract |
|
Twin pregnancy consisting of complete hydatidiform mole [H-mole] and a coexisting fetus occurs in an estimated incidence of one per 22,000-100,000. This entity is different from a partial molar pregnancy because there are two separate conceptuses with a normal placenta in one twin and a complete molar gestation in the other. Because of the high risk of persistent or metastatic gestational trophoblastic tumor, the diagnosis and management of twin pregnancy consisting of complete H-mole and a coexisting fetus is very important. However, there are limited data to guide the antenatal management of this pregnancy. The incidence of this twin pregnancy with complete H-mole and a coexisting fetus after in vitro fertilization and embryo transfer [IVF-ET] is not increased compared with that of general population, however, with the more widespread use of ovulation induction, it is expected that multiple gestations containing complete H-mole will occur with increasing frequency. Because of their propensity to develop medical complications and persistent gestational trophoblastic tumor, patients with complete H-mole and a coexisting fetus remain an imposing clinical challenge. We present an unusual pregnancy with complete H-mole and a coexisting fetus that occured following IVF-ET and was evacuated at 21 weeks gestation and developed into nonmetastatic gestational trophoblastic disease that required the MTX-CF [methotrexate-citrovorum factor] chemotherapy to achieve complete remission with brief review of literatures. |
| Key Words:
Twin pregnancy, Complete hydatidiform mole, A coexisting fetus |
|
Full text via DOI
Download Citation
