Recurrent Anencephaly in A Same Pregnant Women: Report of Two Cases.

Yoo, Yong Gyun; Kim, Jae Wook; Kim, Sei Kwang; Kim, Young Han; Yeon, Jung Eun; Sohn, Yong Seok; Jung, Young Nae; Lee, Yun Jung

Case Report

Korean Journal of Obstetrics & Gynecology 1999;42(3):637-640.
Published online January 1, 2001.

Recurrent Anencephaly in A Same Pregnant Women: Report of Two Cases.

Yong Gyun Yoo, Jae Wook Kim, Sei Kwang Kim, Young Han Kim, Jung Eun Yeon, Yong Seok Sohn, Young Nae Jung, Yun Jung Lee

Abstract

The etiology of neural tube defects, a category encompassing spina bifida, anencephaly and encephalocele, remains highly controversial and unclear, However, there is overwhelming evidence supporting a multifactorial etiology for this group of defects. Recent studies have shown that folic acid supplements taken periconceptionally can reduce a woman's risk of having a child with a neural tube defect. Qenetic screening could identify women who will require folic acid supplements periconceptionally to reduce their risk of having a child with a neural tube defects. Recently, we encountered two cases of recurrent anencephaly that had occurted in a same pregnant woman in our hospital. We report these two cases with brief review of the literatures.

Key Words: Neural tube defect, anencephaly, folic acid