A Case of Wernicke - Korsakoff Syndrome Associated with Hyperemesis Gravidarum.

Yang, Soon Ha; Roh, Cheong Rae; Lee, Jae Sung; Moon, Heui Soo; Cheung, Jae Hyun

Case Report

Korean Journal of Obstetrics & Gynecology 1999;42(2):429-431.
Published online January 1, 2001.

A Case of Wernicke - Korsakoff Syndrome Associated with Hyperemesis Gravidarum.

Soon Ha Yang, Cheong Rae Roh, Jae Sung Lee, Heui Soo Moon, Jae Hyun Cheung

Abstract

A 24-year-old pregnant woman started to have severe hyperemesis gravidarum at 6 weeks' gestation. Six weeks later, dizziness, ataxia, visual disturbance, diplopia and confusion were developed. On admission, she presented ophthalmoplegia, nystagmus, deaeased tendon reflex, intention tremor, ataxia, confusion and memory disturbance. She was diagnosed to Wernicke-Korsakoff syndrome and 100mg of thiamine was administered intravenously daily till 28 weeks gestation and then intramuscularly. Her ocular symptns, together with neurological signs, were gradually improved. Memory disturbance slightly improved but remained at the time of delivery. The case will be presented in more details with a brief revie of literatures.

Key Words: Hyperemesis gravidarum, Wernicke-Korsakoff syndrome