Myotonic Dystrophy in Pregnancy complicated with Preterm Labor and Congestive Heart Failure.

Yang, Soon Ha; Roh, Cheong Rae; Chung, Jae Hyun; Moon, Zong Soo; Moon, Jong Taek; Kim, B Joon

Case Report

Korean Journal of Obstetrics & Gynecology 1999;42(2):408-411.
Published online January 1, 2001.

Myotonic Dystrophy in Pregnancy complicated with Preterm Labor and Congestive Heart Failure.

Soon Ha Yang, Cheong Rae Roh, Jae Hyun Chung, Zong Soo Moon, Jong Taek Moon, B Joon Kim

Abstract

Myotonic dystrophy is an autosomal-dominantly inherited neuromuscular disorder characterized by slowly progressive muscular dystrophy, muscle weakness and myotonia. The clinical features may vary from just cataracts to involvement of multiple organ systems such as various muscles, heart, lung and intestine. During pregnancy and delivery, serious maternal and obstetrical complications may occur. The myotonia is often aggravated during pregnancy and it leads to obstetrical complications such as fetal loss, preterm premature delivery, hydrops, in-utero fetal death, difficulties in fetal expulsion, postpartum hemorrhage and/or anesthetic accidents. The affected neonate may display severe hypotonia, facial displegia and respiratory distress. This report presents a woman with myotonic dystrophy complicated with congestive heart failure and preterm delivery during pregnancy.

Key Words: Myotonic dystrophy, Pregnancy, Congestive heart failure, Preterm delivery