Predictive Value of Serum beta-hCG Level in Pregnancies following In Vitro Fertilization and Embryo Transfer.

Park, K H; Han, H D; Oh, J H; Hong, M; Lee, Y J; Han, S W

Original Article

Korean Journal of Obstetrics & Gynecology 1998;41(10):2557-2561.
Published online January 1, 2001.

Predictive Value of Serum beta-hCG Level in Pregnancies following In Vitro Fertilization and Embryo Transfer.

K H Park, H D Han, J H Oh, M Hong, Y J Lee, S W Han

Abstract

Serum level of beta-subunit of human chorionic gonadotropin (beta-hCG) at the post-ET day 16 was studied to evaluate its predictability of pregnancy outcome in 165 patients in vitro fertilization and embryo transfer (IVF-ET), which included 63 singleton pregnancies, 40 multiple pregnancies, 37 preclinical abortions, 20 clinical abortions and 5 ectopic pregnancies. In comparison to normal singleton pregnancies, multiple pregnancies showed significantly higher serum beta-hCG level and preclinical abortions showed significantly lower serum beta-hCG level, but Clinical abortions and ectopic pregnancies didn`t showed statistical significance level of serum beta-hCG. In conclusion, determination of serum beta-hCG level at post-ET day 16 is a useful tool for the prediction of preclinical abortions and multiple pregnancies.

Key Words: IVF-ET, Serum beta hCG