Recurrent Fetal Losses and Autoantibody: Successful Treatment with Intravenous Immunoglobulin.

Ryu, H M; Kim, M Y; Kim, E S; Noh, G W; Jang, H C; Jun, J Y

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Korean Journal of Obstetrics & Gynecology 1998;41(8):2229-2232.
Published online January 1, 2001.

Recurrent Fetal Losses and Autoantibody: Successful Treatment with Intravenous Immunoglobulin.

H M Ryu, M Y Kim, E S Kim, G W Noh, H C Jang, J Y Jun

Abstract

There is an association between the presence of autoantibody and the occurrence of repeated second trimester fetal losses. Many uncontrolled studies have reported with steroids, low dose aspirin, heparin, or their combination. Also, treatment failures have been reported with most of these therapeutic regimens. Immunoglobulins play a central role in immune regulation. We present a successful outcome by intravenous immunoglobulines in pregnant women with previous recurrent second trimester fetal losses and autoantibody with a brief review of the literatures.

Key Words: Autoantibody, Recurrent second trimester fetal loss, Intravenous immunoglobulin

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