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Korean Journal of Obstetrics & Gynecology 1998;41(8):2079-2083.
Published online January 1, 2001.
Vaginal Administered Misoprostol Versus Laminaria Insertion for Cervical Dilation in First Trimester Pregnancy Interruption.
I S Rhee, J J Lee, S D Choi, H H Lee, K H Nam, K H Lee
To make a comparison of the effect of cervical dilatation for therapeutic abortion between vaginal administration of misoprostol and laminaria insertion into the cervix. METHODS: Forty-five women received 100 microgram of misoprostol as powder in the posterior vaginal fornix and laminaria were inserted into the cervix in forty-one women before curettage in first trimester pregnancy. We compared the effect of cervical dilatation and side effects. RESULTS: The effect of cervical dilatation was not statistically different between the groups (8.2+/-2.5 versus 8.7+/-1.6 mm). The occurence of nausea, vomiting, diarrhea were none in both groups. Low abdominal pain was less frequent in the women receiving vaginal misoprostol than in those laminaria insertion (6.7% versus 22.0%). Vaginal bleeding was more frequent in the women receiving misoprostol than in those laminaria insertion (35.6% versus 22.0%). But the amount of vaginal bleeding was only minimal, it was not clinically significant. CONCLUSION: Vaginal administered misoprostol is as effective as laminaria insertion for cervical dilatation and curettage in the first trimester pregnancy.
Key Words: Misoprostol, Laminaria, Cervical dilatation, Abortion

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