A Case of Premature Ovarian Failure Associated with 46, X, t ( X ; 11 ) in Secondary Amenorrheic Patient.

Nam, Y S; Lee, S H; Kwak, I P; Yoon, T K; Cha, K Y

Case Report

Korean Journal of Obstetrics & Gynecology 1998;41(2):617-621.
Published online January 1, 2001.

A Case of Premature Ovarian Failure Associated with 46, X, t ( X ; 11 ) in Secondary Amenorrheic Patient.

Y S Nam, S H Lee, I P Kwak, T K Yoon, K Y Cha

Abstract

Premature ovarian failure is a condition causing amenorrhea, hypoestrogenism, and elevated gonadotropins in women younger than 40 years. A karytype should be performed as part of basic laboratory evaluation for all patients with premature ovarian failure and prodromal premature ovarian failure. Although it has been suggested that the karyotype be omitted in patients who are either parous or older than 35 years, neither age nor parity rules out a chromosomal abnormality. We have experienced a case of premature ovarian failure in secondary amenorrheic patient showing chromosomal abnormality. So we report this case with a brief review of literatures.

Key Words: Premature ovarian failure, Secondary amenorrhea, Chromosomal abnormality