Two cases of primary malignant melanoma of vagina.

Cheon, Juyoung; Lee, Soo Jeong; Kim, Sul Ah; Choi, Jeong In; Park, Sung Taek; Hur, Sooyoung

doi:2012.55.12.1020

Obstet Gynecol Sci > Volume 55(12); 2012 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2012;55(12):1020-1025.
DOI: https://doi.org/10.5468/KJOG.2012.55.12.1020 Published online December 18, 2012.

Two cases of primary malignant melanoma of vagina.

Juyoung Cheon, Soo Jeong Lee, Sul Ah Kim, Jeong In Choi, Sung Taek Park, Sooyoung Hur

¹Department of Obstetrics and Gynecology, The Catholic University of Korea College of Medicine, Seoul, Korea. Hursy@catholic.ac.kr
²Department of Obstetrics and Gynecology, Hallym University College of Medicine, Seoul, Korea.

Abstract

Primary malignant melanoma of the vagina is extremly rare disease. This disease is one of non-cutaneous melanomas and accounts for 0.3% of all malignant melanomas. The most common symptoms is vaginal bleeding because the disease is usually in advanced stage at first visit. An appropriate and effective treatment protocol has not been established. The prognosis is poorer than those of other vulvar melanomas. It has been known the tumor size is the most important prognostic factor determining the survival outcome. We reported two cases of primary malignant melanoma of the vagina with review of literature.

Key Words: Primary malignant melanoma, Vagina, Immunohistochemistry