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Obstet Gynecol Sci > Volume 55(12); 2012 > Article
Korean Journal of Obstetrics & Gynecology 2012;55(12):935-939.
DOI: https://doi.org/10.5468/KJOG.2012.55.12.935    Published online December 18, 2012.
Serum anti-Mullerian hormone levels in the patients with ovarian endometriosis undergoing surgical treatment.
Jea Ra Lee, Min Young Lee, Hye Woen Park, Sun Wha Cha, Chan Woo Park, Jin Yeong Kim, Kwang Moon Yang, In Ok Song, Mi Kyoung Koong, Inn Soo Kang, Hye Ok Kim
Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea. ok58163@hanmail.net
Abstract
OBJECTIVE
To evaluate the difference of serumanti-Mullerian hormone (AMH) levels in women between undergoing previous ovarian surgery with endometriosis and controls. METHODS: We reviewed medical records and evaluated the serum AMH levels of 217 women (26-40 years old) between March 2010 and January 2011, retrospectively. One hundred five patients were previously undergone the ovarian surgery of endometriosis (study group) and 112 women has never undergone ovarian surgery as controls (control group). Exclusion criteria was following factors: irregular menstruation, polycystic ovary syndrome, high BMI (> or =30 kg/m2), other endocrine disease. RESULTS: The mean age in study group was not different with control group (32.5 +/- 3.6 vs. 33.0 +/- 3.8 year). The mean serum AMH levels significantly lower in the study group than in control (2.82 +/- 2.4 ng/mL vs. 3.82 +/- 2.8 ng/mL, P=0.005). When we analyzed the serum AMH levels according to age groups, the patients above 31 years showed significantly lower levels than control (31-35 years, 2.41+/-1.7 ng/mL vs. 3.84 +/- 2.6 ng/mL, P=0.005; 36-40 years, 1.36 +/- 2.0 ng/mL vs. 2.68 +/- 2.7 ng/mL, P=0.018) The serum AMH levels didn't show any statistical difference in aspect of bilaterality, endometriosis stage, cyst size (> or =6 cm). CONCLUSION: We could consider relatively low serum AMH levels in patients with ovarian endometriosis after surgical treatment.
Key Words: Anti-Mullerian hormone, Ovarian endometriosis, Endometriosis, Ovarian reserve


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