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Obstet Gynecol Sci > Volume 55(12); 2012 > Article
Korean Journal of Obstetrics & Gynecology 2012;55(12):920-928.
DOI: https://doi.org/10.5468/KJOG.2012.55.12.920    Published online December 18, 2012.
Age-related distribution of anti-Mullerian hormone levels in 2,879 Korean women with regular menstruation.
Jee Eun Lee, Dong Soo Park, Mi La Kim, Bo Sung Yoon, Taejong Song, Mi Kyoung Kim, Seok Ju Seong, Young Ju Kim
1Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Korea. mila76@naver.com
2Department of Statistics, Kangwon National University, Chuncheon, Korea.
Abstract
OBJECTIVE
To determine the age-related distribution of anti-Mullerian hormone (AMH) in Korean women with regular menstruation who visited fertility center. METHODS: Between May 2010 and April 2011, serum AMH levels on day 2-3 of a spontaneous menstrual cycle were evaluated in 2,879 women of reproductive age ranging from 25 to 45 years old, retrospectively. RESULTS: The mean age was 34.2 +/- 4.3 years. The overall mean AMH value was 3.54 +/- 2.66 ng/mL (median, 2.9 ng/mL). Serum AMH level showed an age-dependent distribution and correlated negatively with age. Among multiple regression models, the quadratic model was most appropriated to describe the relationship between AMH and age (logAMH = -1.442 + 0.225 x age-0.004 x age2). CONCLUSION: Our data showed reference values of serum AMH in Korean infertile women with regular menstruation. These values can be used as an important information of ovarian reserve for infertility patients and clinicians.
Key Words: Anti-Mullerian hormone, Regular menstruation, Reference values


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