A case of juvenile xanthogranuloma involving skin and multiple systemic organs in a fetus.

Kim, Eunjin; Kim, Hye Young; Lee, Jae Ho; Park, Chan Wook; Park, Joong Shin; Jun, Jong Kwan

doi:2012.55.10.756

Obstet Gynecol Sci > Volume 55(10); 2012 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2012;55(10):756-760.
DOI: https://doi.org/10.5468/KJOG.2012.55.10.756 Published online October 10, 2012.

A case of juvenile xanthogranuloma involving skin and multiple systemic organs in a fetus.

Eunjin Kim, Hye Young Kim, Jae Ho Lee, Chan Wook Park, Joong Shin Park, Jong Kwan Jun

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea. jsparkmd@snu.ac.kr

Abstract

Juvenile xanthogranuloma is a benign histiocytic proliferative disorder. It typically presents as a solitary, benign, rapidly growing cutaneous tumor that may regress spontaneously. Most of juvenile xanthogranuloma occur in infants and young children. We had experienced a case of juvenile xanthogranuloma in a fetus which involves multiple systemic organs. On prenatal ultrasonography, the fetus presented with pulmonary, perineal and hepatic nodules. The neonate was diagnosed with juvenile xanthogranuloma by the cutaneous and perineal nodule biopsy after birth. The neonate outpatient follow-up shows spontaneous regression without specific treatment. So we report a case with a brief review of the literature.

Key Words: Juvenile xanthogranuloma, Fetus, Systemic involvement, Multiple, Congenital