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Korean Journal of Obstetrics & Gynecology 1997;40(2):429-433.
Published online January 1, 2001.
A Case of Wernicke-Korsakoff Syndrome Associated with Hyperemesis Gravidarum.
Jong Cheol Lee, Eun Hwan Jeong, Jae Sook Roh, Cyi Seok Ahn, Hak Soon Kim
Department of Obstetrics and Gynecology, Chungbuk National University College of Medicine, Cheongju, Korea.
Abstract
Thiamine deficiency is known to lead to certain neurological sequelae including Wernicke-Korsakoff syndrome. Signs attributable to this condition include ataxia, ophthalmoplegia, nystagmus, and mental confusion. The prompt use of thiamine prevents progression of the disease and reverses those lesions that have not yet progressed to the point of fixed structual change. We have experienced a case of Wernicke-Korsakoff syndrome associated with hyperemesis gravidarum, which seemed to be developed by prolonged thiamine-free dextrose therapy, we emphasise the need for thiamine supplementation in hyperemesis gravidarum patient.
Key Words: Wernicke-Korsakoff syndrome, Hyperemesis gravidarum, Thiamine


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