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Obstet Gynecol Sci > Volume 55(6); 2012 > Article
Korean Journal of Obstetrics & Gynecology 2012;55(6):378-383.
DOI: https://doi.org/10.5468/KJOG.2012.55.6.378    Published online June 16, 2012.
25-hydroxyvitamin D levels and body mass index in healthy postmenopausal women.
Sun Young Jang, Ji Young Lee, Jae Man Bae, Chulmin Lee, Sung Nam Hong, Ari Kim, Heung Yeol Kim
1Department of Obstetrics and Gynecology, Kosin University College of Medicine, Busan, Korea. hykyale@yahoo.com
2Department of Obstetrics and Gynecology, Konkuk University School of Medicine, Seoul, Korea.
3Department of Obstetrics and Gynecology, Inje University Sanggye Paik Hospital, Seoul, Korea.
4Department of Obstetrics and Gynecology, Samsung Changwon Hospital, Sungkyungkwan University School of Medicine, Changwon, Korea.
5Institute of Wonkwang Medical Science, Wonkwang University College of Medicine, Iksan, Korea.
Abstract
OBJECTIVE
Obesity is associated with alterations in vitamin D (VtD) system. We evaluated the correlation between VtD level and body mass index (BMI), a standard for the evaluation of obesity in postmenopausal women. METHODS: To study the relationship between VtD levels and obesity, we recruited 310 healthy postmenopausal women between January 2005 and March 2011 and analyzed the correlation between BMI and serum 25-hydroxyvitamin D (25-OH-VtD) level. We also analyzed the relationship between serum VtD level and bone health status such as bone mineral density measured by dual-energy X-ray absorptiometry, bone turnover marker, and parathyroid hormone (PTH). RESULTS: With a cut-off level for VtD deficiency at 30 ng/mL, 98.9% patients showed a VtD deficiency, while 87.8% patients showed a vitamin D deficiency with a 20-ng/mL cut-off level. VtD levels had no significant correlation with age, height, weight, BMI, or bone turnover markers. PTH level and serum 25-OH-VtD level showed a negative correlation. VtD level showed negative correlation with BMI, but statistically not significant. CONCLUSION: In this study, most of postmenopausal women (more than 87.8%) had a VtD deficiency, and VtD level showed negative correlation with BMI, but was not statistically significant.
Key Words: Vitamin D, Body mass index, Obesity, Postmenopause


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