Obstet Gynecol Sci > Volume 63(6); 2020 > Article |
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Characteristic | Recurrence | No recurrence |
---|---|---|
High LDH (≥250) and low NLR (≥4) | 37 | 21 |
High LDH (≥250) or high NLR (≥4) | 46 | 37 |
Low LDH (<250) and low NLR (<4) | 27 | 51 |
Variable | No. |
Univariate analysis |
Multivariate analysis |
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Model 1a) |
Model 2b) |
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HR | 95% CI | P-value | HR | 95% CI | P-value | HR | 95% CI | P-value | ||
Group A vs. group B | 222 | 0.816 | 0.558-1.192 | 0.292 | - | - | ||||
FIGO stage | 222 | - | ||||||||
I | ||||||||||
II/III/IV | 17.041 | 6.926-41.929 | <0.001 | 13.386 | 5.065-35.381 | <0.001 | ||||
Histology | 222 | - | ||||||||
High-grade serous | ||||||||||
Others | 3.527 | 2.248-5.535 | <0.001 | 1.050 | 0.632-1.743 | 0.851 | ||||
Cytoreduction | 222 | - | ||||||||
R0 | ||||||||||
R1/2 | 3.977 | 2.686-5.886 | <0.001 | 2.111 | 1.415-3.151 | <0.001 | ||||
Age (per 1) | 222 | 1.022 | 1.005-1.038 | 0.009 | - | 1.004 | 0.987-1.021 | 0.674 | ||
WBC (per 1,000) | 222 | 1.016 | 0.956-1.079 | 0.613 | - | - | ||||
Neutrophil (per 1,000) | 219 | 1.021 | 0.958-1.088 | 0.517 | - | - | ||||
Lymphocyte (per 1,000) | 219 | 0.905 | 0.647-1.264 | 0.557 | - | - | ||||
NLR (per 1) | 219 | 1.008 | 0.968-1.050 | 0.698 | − | - | ||||
Platelet (per 1) | 222 | 1.002 | 0.996-1.008 | 0.498 | - | - | ||||
PLR (per 1) | 219 | 1.000 | 1.000-1.001 | 0.158 | - | - | ||||
CRP (per 1) | 222 | 1.006 | 0.975-1.039 | 0.705 | - | - | ||||
LDH (per 1) | 222 | 1.001 | 1.000-1.002 | 0.019 | 1.001 | 1.000-1.002 | 0.019 | 1.000 | 0.998-1.001 | |
Glucose (per 1) | 221 | 0.994 | 0.986-1.003 | 0.223 | - | - | ||||
TC (per 1) | 186 | 0.998 | 0.993-1.002 | 0.349 | - | - | ||||
TG (per 1) | 126 | 1.000 | 0.996-1.004 | 0.912 | - | - | ||||
HDL (per 1) | 120 | 0.999 | 0.986-1.012 | 0.835 | - | - | ||||
LDL (per 1) | 124 | 0.999 | 0.991-1.006 | 0.718 | - | - | ||||
CA125 (per 1) | 219 | 1.000 | 1.000-1.000 | 0.004 | - | - | ||||
Log CA125 (per 1) | 219 | 1.817 | 1.435-2.301 | <0.001 | - | - |
Bold words represent statistical significance.
HR, hazard ratio; CI, confidence ratio; FIGO, International Federation of Gynecology and Obstetrics; WBC, white blood cell count; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte rate; CRP, C-reactive protein; LDH, lactate dehydrogenase; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; CA125, cancer antigen 125.
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