Ovarian mixed germ cell tumor in a patient with 45,X/46,X,+mar mosaic Turner's syndrome.

Kim, Hae Kyung; Song, Mi Hyun; Ahn, Byul Nim; Choi, Jong Yoon; Oh, Hoon Kyu; Lee, Tae Sung

doi:2011.54.8.468

Obstet Gynecol Sci > Volume 54(8); 2011 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2011;54(8):468-473.
DOI: https://doi.org/10.5468/KJOG.2011.54.8.468 Published online August 1, 2011.

Ovarian mixed germ cell tumor in a patient with 45,X/46,X,+mar mosaic Turner's syndrome.

Hae Kyung Kim, Mi Hyun Song, Byul Nim Ahn, Jong Yoon Choi, Hoon Kyu Oh, Tae Sung Lee

¹Department of Obstetrics and Gynecology, Catholic University of Daegu School of Medicine, Daegu, Korea. leets@cu.ac.kr
²Department of Pathology, Catholic University of Daegu School of Medicine, Daegu, Korea.

Abstract

We report a case that mixed germ cell tumor developed in an 18-year-old girl with 45,X/46,X,+mar mosaic Turner's syndrome. Molecular biological studies showed that the patient's DNA contained a fragment of Y chromosome. The patient underwent an operation and chemotherapy, and until now there is no evidence of recurrence. A presence of Y chromosome component should be evaluated in case a marker chromosome is found in a woman with Turner's syndrome.

Key Words: Turner syndrome, Marker chromosome, Germ cell tumor