Prenatal diagnosis of caudal regression syndrome: A case report.

Park, Ji Eun; Cho, In Ae; Lee, Dong Hee; Shin, Jeong Kyu; Lee, Soon Ae; Lee, Jong Hak; Paik, Won Young

doi:2011.54.5.265

Obstet Gynecol Sci > Volume 54(5); 2011 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2011;54(5):265-268.
DOI: https://doi.org/10.5468/KJOG.2011.54.5.265 Published online May 1, 2011.

Prenatal diagnosis of caudal regression syndrome: A case report.

Ji Eun Park, In Ae Cho, Dong Hee Lee, Jeong Kyu Shin, Soon Ae Lee, Jong Hak Lee, Won Young Paik

¹Department of Obstetrics and Gynecology, Gyeongsang National University School of Medicine, Jinju, Korea. wypaik@gnu.ac.kr
²Gyeongsang Institute of Health Sciences, Gyeongsang National University, Jinju, Korea.

Abstract

Caudal regression syndrome is rare congenital defect, characterized by the absence of the sacrum, and defects of variable portion of lumbar spine, associated with anomalies from different systems. Although hyperglycemia related to maternal diabetes, genetic predisposition, teratogens, and vascular anomalies altering blood flow have been hypothesized to play a role in its pathogenesis, but the cause of this rare condition is not clear. We report a case of caudal regression syndrome diagnosed by prenatal ultrasonography at 16 weeks of gestation.

Key Words: Caudal regression syndrome, Prenatal ultrasonography