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Case Report
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Korean J Obstet Gynecol. 2009;52(3):372-376. Published online March 1, 2009.
- A case of microinvasive Paget's disease of the vulva: Treatment of positive resection margin with topical 5-FU cream application.
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Ho Jeong Kang, Chul Min Park, Soon Sup Shim, Young Soo Son, Sung Yob Kim
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Department of Obstetrics and Gynecology, Cheju National University, College of Medicine, Jeju, Korea. kimsy@cheju.ac.kr
- Abstract
- Extramammary Paget's disease of the vulva is a rare lesion that accounts for 1~2% of vulvar neoplasms. Paget's disease often has a microscopic extension beyond the gross lesion and shows a multifocal distribution. Positive resection margin is common. We applied 5-FU cream on the lesion who had a positive resection margin. There was no residual lesion on multiple punch biopsies after 5-FU cream treatment three months later. And there has been no evidence of disease recurrence in the 12-month follow-up period. We experienced a case of effective treatment with 5-FU cream in microinvasive Paget's disease of the vulva with positive resection margin. We present it with a brief review of literatures.
Keywords :Extramammary Paget's disease of the vulva;5-fluorouracil (5-FU)
