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Case Report
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Korean J Obstet Gynecol. 2008;51(11):1337-1341. Published online November 1, 2008.
- A case of Larsen syndrome.
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Jin Sub Kim, Seung Hyun Kim, Jeung Hyun Kim, Chan Hee Jin, Hyun Young Kim, Young Rae Song, Kwan Young Oh
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Department of Obstetrics & Gynecology, Eulji University Hospital, Daejeon, Korea. ohky5@eulji.ac.kr
- Abstract
- Larsen syndrome is a rare congenital skeletal malformation (1 in 100,000 births) caused by a generalized mesenchymal connective tissue disorder. This disorder leads to a broad spectrum of anomalies. Major diagnostic criteria are multiple dislocations of large joints (especially knees), short metacarpals with cylindrical nontapering fingers and craniofacial abnormalities. Clinical variations range from mild clinical expression to lethal forms. Sporadic occurrence as well as autosomal dorminant and recessive inheritance are described.
Keywords :Larsen syndrome
