Obstetrics & Gynecology Science

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Case Report
Korean J Obstet Gynecol. 2006;49(9):1993-1998. Published online September 1, 2006.
A case of low-grade endometrial stromal sarcoma with multiple metastasis.
Han Byoul Cho, Jae Hoon Kim, Soon Won Hong, Hyun Joon Lee, Min Kyoung Kim, Sung Hoon Kim, Young Tae Kim, Jae Wook Kim
1Department of Obstetrics and Gynecology, Yong Dong Severance Hospital, Korea. jaehoonkim@yumc.yonsei.ac.kr
2Department of Pathology, Yong Dong Severance Hospital, Korea.
3Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University Collage of Medicine, Seoul, Korea.
Abstract
Uterine sarcomas are rare tumors of mesodermal origin and constitute 2-6% of uterine malignancies. They are classified into leiomyosarcoma (LMS), malignant mixed mullerian tumors (MMMTs), and endometrial stromal sarcoma (ESS) by histologic types. Endometrial stromal sarcomas account for about 7-15% of uterine sarcomas, about 0.2% of female genital tract malignancies. Endometrial stromal sarcomas are divided into endometrial stromal nodule, low-grade endometrial stromal sarcoma, and high-grade endometrial stromal sarcoma on the basis of mitotic activity and vascular invasion. Clinical outcome of low-grade endometrial sarcoma is better than that of high-grade endometrial stromal sarcoma and has a propensity for slow metastasis. We have experienced a case of low-grade endometrial stromal sarcoma with multiple metastasis in a 41-year-old woman and was treated by surgical resection and combination chemotherapy, which is presented with a review of brief literature.

Keywords :Low-grade endometrial stromal sarcoma (ESS);Multiple metastasis

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